Expression of cystic fibrosis transmembrane conductance regulator in human endometrium | Zendy

Xiaoying Zheng | Zendy; Guian Chen | Zendy; Haiyan Wang | Zendy

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Expression of cystic fibrosis transmembrane conductance regulator in human endometrium

Author(s) -

Xiaoying Zheng,

Guian Chen,

Haiyan Wang

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh507

Subject(s) - cystic fibrosis transmembrane conductance regulator , endometrium , cystic fibrosis , endocrinology , medicine , in situ hybridization , forskolin , biology , western blot , messenger rna , secretory protein , uteroglobin , northern blot , secretion , microbiology and biotechnology , gene , stimulation , biochemistry , lung

As a cAMP-regulated Cl- channel, cystic fibrosis transmembrane conductance regulator (CFTR) plays a critical role in the active secretion of electrolytes and fluid in epithelial cells. Women with CFTR gene mutations are less fertile, generally assumed to be due to cervical factors. However, there is little known about CFTR protein expression in human endometrium and its possible roles in reproduction.

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