Human chorionic gonadotropin and growth factors at the embryonic–endometrial interface control leukemia inhibitory factor (LIF) and interleukin 6 (IL-6) secretion by human endometrial epithelium
Author(s) -
Sophie Perrier d'HAUTERIVE,
C Charlet-Renard,
Sarah Berndt,
Michel Dubois,
Carine Munaut,
Frédéric Goffin,
M.-T. Hâgelstein,
Agnès Noël,
A Hazout,
Jean Michel Foidart,
Vincent Geenen
Publication year - 2004
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh450
Subject(s) - leukemia inhibitory factor , human chorionic gonadotropin , medicine , endocrinology , blastocyst , secretion , biology , gonadotropin , chemistry , cytokine , embryogenesis , embryo , interleukin 6 , microbiology and biotechnology , hormone
The elucidation of the molecular mechanisms by which the embryo contributes to its implantation is an area of extensive research. The main objective of this study was to investigate the pattern of leukemia inhibitory factor (LIF) and interleukin-6 (IL-6) secretion by human endometrial epithelium, and their regulation by human chorionic gonadotropin (hCG) and other growth factors present at the embryonic-endometrial interface.
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