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The effect of HRT on cerebral haemodynamics and cerebral vasomotor reactivity in post-menopausal women
Author(s) -
C Bain,
Matthew R. Walters,
Kennedy R. Lees,
Mary Ann Lumsden
Publication year - 2004
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh396
Subject(s) - medicine , middle cerebral artery , placebo , transcranial doppler , vasomotor , dydrogesterone , menopause , norethisterone , anesthesia , estrogen , ischemia , population , alternative medicine , environmental health , pathology , research methodology
Cerebral vasomotor reactivity (CVR) is an index of cerebrovascular dilatory capacity which can readily be assessed using trans-cranial Doppler ultrasound. Impaired CVR is associated with elevated risk of stroke. We performed a randomized, double-blind placebo-controlled trial to investigate the effect of two HRT preparations upon CVR.

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