Comparison of the aneuploidy frequency in embryos derived from testicular sperm extraction in obstructive and non-obstructive azoospermic men | Zendy

Peter Platteau | Zendy; C. Staessen | Zendy; A. Michiels | Zendy; Herman Tournaye | Zendy; A. Van Steirteghem | Zendy; I. Liebærs | Zendy; P. Devroey | Zendy

Open Access

Comparison of the aneuploidy frequency in embryos derived from testicular sperm extraction in obstructive and non-obstructive azoospermic men

Author(s) -

Peter Platteau,

C. Staessen,

A. Michiels,

Herman Tournaye,

A. Van Steirteghem,

I. Liebærs,

P. Devroey

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh306

Subject(s) - aneuploidy , intracytoplasmic sperm injection , azoospermia , obstructive azoospermia , testicular sperm extraction , andrology , sperm retrieval , gynecology , infertility , male infertility , sperm , medicine , prospective cohort study , embryo , pregnancy rate , spermatogenesis , biology , pregnancy , genetics , chromosome , gene

The use of ICSI has been a major breakthrough in the treatment of male infertility. Even azoospermic patients with focal spermatogenesis in the testis (not sufficient to spill over into the ejaculate) may benefit from the technique. Previous reports suggest a higher pregnancy rate after ICSI treatment in patients with obstructive azoospermia (OA) compared to their non-obstructive azoospermia (NOA) counterparts, which could be due to a higher aneuploidy frequency in the embryos of the latter group. We therefore conducted a prospective cohort study to compare the aneuploidy frequency of the screened embryos between the two groups.

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