Open AccessProliferation of ovarian theca-interstitial cells is modulated by antioxidants and oxidative stress
Author(s) -
Antoni J. Dulęba
Publication year - 2004
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh299
Subject(s) - oxidative stress , xanthine oxidase , cell growth , reactive oxygen species , endocrinology , medicine , superoxide dismutase , chemistry , biology , biochemistry , enzyme
Maintenance of ovarian homeostasis requires precise regulation of proliferation of thecal- interstitial (T-I) cells. Recent evidence indicates that oxidative stress and antioxidants modulate proliferation of various tissues under both physiological and pathological conditions. This study evaluated the effects of oxidative stress and antioxidants on T-I proliferation.
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