Expression of androgen receptors in upper human fetal reproductive tract | Zendy

Yasmin Sajjad | Zendy

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Expression of androgen receptors in upper human fetal reproductive tract

Author(s) -

Yasmin Sajjad

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh295

Subject(s) - mesonephric duct , mesenchyme , mesonephros , biology , androgen receptor , mullerian ducts , endocrinology , medicine , fetus , andrology , androgen , epithelium , kidney , uterus , hormone , gene , pregnancy , genetics , embryonic stem cell , prostate cancer , cancer

Androgens play a key role in human fetal development. All androgens act through a single intracellular androgen receptor (AR), which is encoded by a single copy gene on the X chromosome. ARs are expressed as early as 9 weeks in the epithelium and mesenchyme of the urogenital sinus, paramesonephric (Müllerian) and mesonephric (Wolffian) ducts.

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