Open AccessThe recombinant subdomain IIIB of human serum albumin displays activity of gonadotrophin surge-attenuating factor
Author(s) -
Sotiria Tavoulari
Publication year - 2004
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh187
Subject(s) - pichia pastoris , human serum albumin , recombinant dna , secretion , albumin , chemistry , biology , microbiology and biotechnology , biochemistry , gene
Gonadotrophin surge-attenuating factor (GnSAF) is an as yet unidentified ovarian factor that acts on the pituitary to attenuate the pre-ovulatory LH surge. In a previous study, GnSAF bioactivity was proposed to derive, at least in part, from a C-terminal domain (95peptide) of human serum albumin (HSA).
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