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To investigate the effect of pioglitazone on adrenal steroidogenesis in polycystic ovary syndrome (PCOS), we studied 11 obese (two with BMI &gt;25 kg/m(2); nine with BMI &gt;27 kg/m(2)) PCOS women before and after 6 months of treatment at a dose of 45 mg/day.

Effect of pioglitazone treatment on the adrenal androgen response to corticotrophin in obese patients with polycystic ovary syndrome