Open AccessIncreased levels of sperm ubiquitin correlate with semen quality in men from an andrology laboratory clinic population
Author(s) -
Peter Šutovský
Publication year - 2004
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh131
Subject(s) - sperm , semen , andrology , infertility , semen quality , semen analysis , biomarker , male infertility , population , sperm motility , ubiquitin , unexplained infertility , biology , medicine , pregnancy , genetics , environmental health , gene
Ubiquitin, a house-keeping protein that marks other proteins for proteasomal degradation, tags defective sperm during epididymal passage. To establish ubiquitin as a biomarker of human infertility, the present study examines the relationships between sperm ubiquitin content and clinical semen parameters among men from an infertility clinic population with varied aetiologies.