Assessment of ovarian reserve: Is there still a role for ovarian biopsy in the light of new data? | Zendy

Amir Lass | Zendy

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Assessment of ovarian reserve: Is there still a role for ovarian biopsy in the light of new data?

Author(s) -

Amir Lass

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh118

Subject(s) - ovarian cortex , ovarian reserve , follicular phase , biopsy , ovary , medicine , ovarian follicle , ovarian tissue cryopreservation , physiology , biology , gynecology , oncology , ovarian tissue , fertility preservation , pregnancy , fertility , infertility , population , environmental health , genetics

Ovarian reserve depends on the number of primordial follicles in the ovarian cortex. It was suggested that determining the follicular density directly by obtaining ovarian biopsy might be more accurate than current indirect biochemical and ultrasonic tests, especially for women in the later stage of their reproductive life. It might also be important and beneficial for young patients having chemotherapy for malignant disease in whom the ovarian tissue should be considered for reimplantation after recovery. The advantages and pitfalls of obtaining ovarian biopsy in these cases are discussed in light of new emerging data on the natural distribution of primordial follicles in the human ovary and its implications.

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