Influence of HRT on prognostic factors for breast cancer: a systematic review after the Women's Health Initiative trial | Zendy

Caroline Antoine | Zendy

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Influence of HRT on prognostic factors for breast cancer: a systematic review after the Women's Health Initiative trial

Author(s) -

Caroline Antoine

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh112

Subject(s) - observational study , confounding , medicine , breast cancer , women's health initiative , oncology , clinical trial , epidemiology , cancer , gynecology

Mortality due to breast cancer has been reported to be the same or even lower in HRT users than in non-users. This has been attributed to earlier diagnosis and to better prognosis. Nevertheless, more advanced disease in HRT users was reported recently by the Women's Health Initiative (WHI) study. The objective of this study was to assess, using a systematic review of current literature, whether the data of the WHI study are in contradiction to observational data.

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