Laser-assisted zona pellucida thinning prior to routine ICSI | Zendy

Marianne Moser | Zendy

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Laser-assisted zona pellucida thinning prior to routine ICSI

Author(s) -

Marianne Moser

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh093

Subject(s) - zona pellucida , oocyte , andrology , human fertilization , hatching , intracytoplasmic sperm injection , zona , pregnancy , embryo , biology , medicine , in vitro fertilisation , anatomy , zoology , immunology , virus , genetics , viral disease , microbiology and biotechnology

In MII oocytes showing difficult oolemma breakage, ICSI can cause an increase in the degeneration rate. This may be overcome by laser-assisted ICSI using a 5-10 micro m opening in the zona pellucida for injection. However, such a small opening might impair the hatching process, especially if assisted hatching is applied in addition. In order to prevent this, the present study used routine injection through an area of zona pellucida in which laser zona thinning had been applied, providing for both a reduced mechanical stress to the oocyte and assisted hatching.

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