Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility
Author(s) -
Mohamed Moustafa,
Rakesh Sharma,
Julie Thornton,
Edward J. Mascha,
Mohammed A Abdel-Hafez,
Anthony J. Thomas,
Ashok Agarwal
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh024
Subject(s) - dna fragmentation , apoptosis , andrology , reactive oxygen species , dna damage , semen , male infertility , infertility , sperm , oxidative stress , biology , comet assay , annexin , dna , microbiology and biotechnology , programmed cell death , endocrinology , medicine , biochemistry , genetics , pregnancy
The aim of this study was to examine the role of apoptosis and reactive oxygen species (ROS) in inducing DNA damage in ejaculated spermatozoa.
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