Familial clustering of impaired spermatogenesis: no evidence for a common genetic inheritance pattern
Author(s) -
Judith Gianotten
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh008
Subject(s) - male infertility , proband , odds ratio , medicine , fertility , infertility , spermatogenesis , semen analysis , etiology , physiology , genetics , gynecology , biology , pregnancy , population , mutation , environmental health , gene
The aetiology of impaired spermatogenesis is unknown in the majority of cases. Evidence of a contribution of genetic factors is still scarce. Therefore, the aim of our study was to assess whether male factor subfertility due to impaired spermatogenesis has a familial component and to test different genetic models of inheritance.
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