Open AccessProlactin acts as a potent survival factor against C2-ceramide-induced apoptosis in human granulosa cells
Author(s) -
Claire M. Perks
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg496
Subject(s) - prolactin , ceramide , apoptosis , corpus luteum , programmed cell death , trypan blue , endocrinology , medicine , biology , granulosa cell , flow cytometry , ovary , microbiology and biotechnology , biochemistry , hormone
The role of prolactin in the regulation of ovarian folliculogenesis and corpus luteal function and in particular its relationship to atresia in these structures is as yet unclear. We established a model of apoptosis in which to examine the actions of prolactin.
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