High singleton live birth rate following classical ovulation induction in normogonadotrophic anovulatory infertility (WHO 2) | Zendy

Marinus J.C. Eijkemans | Zendy

Open Access

High singleton live birth rate following classical ovulation induction in normogonadotrophic anovulatory infertility (WHO 2)

Author(s) -

Marinus J.C. Eijkemans

Publication year - 2003

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deg459

Subject(s) - infertility , ovulation , pregnancy , ovulation induction , polycystic ovary , anovulation , medicine , live birth , pregnancy rate , obstetrics , singleton , gynecology , regimen , fertility , unexplained infertility , population , endocrinology , biology , hormone , diabetes mellitus , insulin resistance , genetics , environmental health

Medical induction of ovulation using clomiphene citrate (CC) as first line and exogenous gonadotrophins as second line forms the classical treatment algorithm in normogonadotrophic anovulatory infertility. Because the chances of success following classical ovulation induction are not well established, a shift in first-line therapy can be observed towards alternative treatment. The study aim was to: (i) reliably assess the probability of singleton live birth following classical induction of ovulation; and (ii) construct a prediction model, based on individual patient characteristics assessed upon standardized initial screening, to help identify patients with poor chances of success.

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