Bioavailability of hCG after intramuscular or subcutaneous injection in obese and non-obese women
Author(s) -
CCY Chan
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg446
Subject(s) - bioavailability , dosing , medicine , pharmacokinetics , intramuscular injection , body mass index , subcutaneous injection , ovulation , area under the curve , endocrinology , obesity , ethinylestradiol , hormone , pharmacology , population , environmental health , research methodology
Obese women require higher gonadotrophin doses for ovarian stimulation and to trigger ovulation. The bioavailability of a drug is affected by its route of administration. Herein, the bioavailability of hCG was compared after intramuscular (i.m.) or subcutaneous (s.c.) injection in obese and non-obese women.
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