Serum IGF-1 concentrations following pituitary desensitization do not predict the ovarian response to gonadotrophin stimulation prior to IVF | Zendy

S.D. Keay | Zendy

Open Access

Serum IGF-1 concentrations following pituitary desensitization do not predict the ovarian response to gonadotrophin stimulation prior to IVF

Author(s) -

S.D. Keay

Publication year - 2003

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deg386

Subject(s) - endocrinology , medicine , follicular phase , stimulation , radioimmunoassay , gonadotropin , desensitization (medicine) , menotropins , ovarian follicle , oocyte , follicle stimulating hormone , ovary , hormone , biology , ovulation induction , ovulation , luteinizing hormone , embryo , receptor , microbiology and biotechnology

Insulin-like growth factor-1 (IGF-1) is known to play a role in ovarian follicular development augmenting the action of FSH. Low intrafollicular concentrations have been detected in women who respond poorly to gonadotrophins. This study addresses the relationship between serum IGF-1 levels following pituitary desensitization and ovarian response to gonadotrophin stimulation.

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