Open AccessHeparan sulphate: a putative decondensing agent for human spermatozoa in vivo
Author(s) -
Marina Romanato
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg354
Subject(s) - heparin , glycosaminoglycan , protamine , sperm , chondroitin , in vivo , sulfation , in vitro , biochemistry , chemistry , hyaluronic acid , pharmacology , biology , andrology , medicine , anatomy , microbiology and biotechnology
Human sperm decondense in vitro upon exposure to heparin and glutathione. The aim of this study was to evaluate whether this decondensing ability of heparin in vitro is related to structural characteristics of the molecule and to test the in-vitro decondensing ability of other glycosaminoglycans.
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