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The births of five Spanish babies from cryopreserved donated oocytes
Author(s) -
N. Fosas
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg297
Subject(s) - cryopreservation , oocyte cryopreservation , andrology , oocyte , human fertilization , biology , gynecology , medicine , embryo , fertility , anatomy , population , fertility preservation , genetics , environmental health
The technique of freezing oocytes is still not widely used. Reasons cited for this include the technique's low efficacy and the risk of aneuploidy. However, the introduction of technical changes (the type and concentration of cryoprotective substances; slow freezing and rapid thawing; and fertilization by ICSI) has led to improved results. We present four pregnancies obtained using mature oocytes (in metaphase II) that had been frozen and thawed. The oocytes were donated by young women who were not patients.

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