Oct-4-expressing cells in human amniotic fluid: a new source for stem cell research?
Author(s) -
AndreaRomana Prusa
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg279
Subject(s) - amniotic epithelial cells , stem cell , amniotic stem cells , embryonic stem cell , biology , induced pluripotent stem cell , amniotic fluid , stem cell marker , adult stem cell , kosr , microbiology and biotechnology , vimentin , immunology , immunohistochemistry , genetics , fetus , pregnancy , gene
It is the hope of investigators and patients alike that in future the isolation of pluripotent human stem cells will allow the establishment of therapeutic concepts for a wide variety of diseases. A major aim in this respect is the identification of new sources for pluripotent stem cells. Oct-4 is a marker for pluripotent human stem cells so far known to be expressed in embryonal carcinoma cells, embryonic stem cells and embryonic germ cells.
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