Open AccessNitric oxide inhibits polyamine-induced apoptosis in the human extravillous trophoblast cell line SGHPL-4
Author(s) -
Philip R. Dash
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg211
Subject(s) - apoptosis , spermine , spermidine , nitric oxide , polyamine , dna fragmentation , microbiology and biotechnology , biology , apoptotic dna fragmentation , programmed cell death , chemistry , biochemistry , endocrinology , enzyme
Polyamines are regulators of proliferation and differentiation in mammalian cells. They are also known to regulate cell survival and apoptosis, although their precise function varies between cell types. We have investigated the effect of polyamines on the apoptosis of human extravillous trophoblasts.
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