Open AccessThe pathogenic role of anti-thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice
Author(s) -
Shelly Tartakover Matalon
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg210
Subject(s) - immunization , thyroglobulin , pregnancy , antibody , active immunization , medicine , immunology , biology , genetics
The presence of antibodies to thyroglobulin (Tg) is associated with fetal loss even in the absence of thyroid dysfunction. The aim of this study was to examine whether active immunization with Tg could elicit anti-Tg autoantibodies and reproductive failure without interfering with thyroid function.
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