Molecular genetic studies of HLA-DRB1 alleles in patients with unexplained recurrent abortion in the Japanese population | Zendy

Koichi Takakuwa | Zendy

Open Access

Molecular genetic studies of HLA-DRB1 alleles in patients with unexplained recurrent abortion in the Japanese population

Author(s) -

Koichi Takakuwa

Publication year - 2003

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deg188

Subject(s) - human leukocyte antigen , abortion , allele , medicine , genetics , population , pregnancy , biology , antigen , gene , environmental health

Recently, evidence that HLA antigens are markers for recurrent spontaneous abortion has gained increased attention. Although the association between HLA class II antigens and patients with unexplained recurrent abortion was elucidated by a large population study in a Caucasian population, such analyses have been conducted in only a small Japanese population. The aim of the present study was to determine whether HLA-DR antigens are associated with patient populations with unexplained recurrent abortion in the Japanese population.

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