Changes in endometrial blood vessels in the endometrium of women with hormone replacement therapy-related irregular bleeding | Zendy

Martha Hickey | Zendy

Open Access

Changes in endometrial blood vessels in the endometrium of women with hormone replacement therapy-related irregular bleeding

Author(s) -

Martha Hickey

Publication year - 2003

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deg171

Subject(s) - hormone replacement therapy (female to male) , endometrium , medicine , menopause , population , blood vessel , endocrinology , breakthrough bleeding , estrogen , urology , environmental health , family planning , research methodology , testosterone (patch)

Irregular bleeding affects up to 60% of hormone replacement therapy (HRT) users. The mechanism of this bleeding is not understood. Reduced endometrial microvascular integrity appears to underlie breakthrough bleeding in pre-menopausal women and the aim of this study was to establish whether similar changes are seen in HRT users and hence to elucidate a possible mechanism of irregular bleeding.

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