An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients | Zendy

Junko Inagaki | Zendy; Mayumi SugiuraOgasawara | Zendy; Motoyoshi Nomizu | Zendy; Mikiya Nakatsuka | Zendy; K. Ikuta | Zendy; Nobuharu Suzuki | Zendy; Keiko Kaihara | Zendy; Kazuko Kobayashi | Zendy; Tatsuji Yasuda | Zendy; Yehuda Shoenfeld | Zendy; Koji Aoki | Zendy; Eiji Matsuura | Zendy

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An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients

Author(s) -

Junko Inagaki,

Mayumi SugiuraOgasawara,

Motoyoshi Nomizu,

Mikiya Nakatsuka,

K. Ikuta,

Nobuharu Suzuki,

Keiko Kaihara,

Kazuko Kobayashi,

Tatsuji Yasuda,

Yehuda Shoenfeld,

Koji Aoki,

Eiji Matsuura

Publication year - 2003

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deg148

Subject(s) - laminin , endometriosis , autoantibody , medicine , infertility , placentation , andrology , gynecology , immunology , antibody , pregnancy , biology , extracellular matrix , fetus , placenta , genetics , microbiology and biotechnology

Laminin-1, a multifunctional glycoprotein of the basement membrane, is thought to be important in embryogenesis, embryonic implantation, and placentation. We recently showed that serum IgG anti-laminin-1 autoantibodies (auto-Abs) are associated with recurrent first-trimester miscarriages. The present study assessed the clinical significance of anti-laminin-1 Abs with infertility, accompanied with or without endometriosis.

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