Open AccessIncreased sperm mitochondrial DNA content in male infertility
Author(s) -
Pascale MayPanloup
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg096
Subject(s) - sperm , biology , andrology , mitochondrial dna , male infertility , infertility , sperm motility , semen , genetics , haplogroup , gene , genotype , medicine , pregnancy , haplotype
There is increasing evidence that mitochondrial DNA (mtDNA) anomalies in sperm may lead to infertility. Point mutations, deletions and the presence of a specific mtDNA haplogroup have been associated with poor sperm quality, but little attention has been paid to the role of mtDNA content.
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