Developmental potential of murine germinal vesicle stage cumulus-oocyte complexes following exposure to dimethylsulphoxide or cryopreservation: loss of membrane integrity of cumulus cells after thawing | Zendy

C.J. Ruppert-Lingham | Zendy

Open Access

Developmental potential of murine germinal vesicle stage cumulus-oocyte complexes following exposure to dimethylsulphoxide or cryopreservation: loss of membrane integrity of cumulus cells after thawing

Author(s) -

C.J. Ruppert-Lingham

Publication year - 2003

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deg071

Subject(s) - cryoprotectant , germinal vesicle , cryopreservation , oocyte , andrology , cumulus oophorus , in vitro maturation , oocyte cryopreservation , biology , embryo , microbiology and biotechnology , fertility preservation , medicine , population , fertility , environmental health

Cumulus cells of the cumulus-oocyte complex (COC) are important in oocyte maturation. Thus, in preserving immature oocytes it is prudent to also preserve their associated cumulus cells. The survival and function of oocytes and their associated cumulus cells was assessed following cryopreservation or exposure to cryoprotectant without freezing.

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