Prenatal exposure to high galactose adversely affects initial gonadal pool of germ cells in rats*
Author(s) -
Santu Bandyopadhyay,
Jana Chakrabarti,
Sayani Banerjee,
Alok K. Pal,
Debashis Bhattacharyya,
S.K. Goswami,
Baidyanath Chakravarty,
S. N. Kabir
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg058
Subject(s) - galactose , germ cell , medicine , endocrinology , wheat germ agglutinin , biology , glycoconjugate , uridine diphosphate , embryo , andrology , enzyme , lectin , biochemistry , microbiology and biotechnology , gene
In rats, prenatal exposure to high concentrations of galactose may contribute to a condition that is equivalent to the premature ovarian failure (POF) component of human galactosaemia. We investigated if development of POF under experimental galactosaemia-like conditions was attributed to impaired germ cell migration.
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