Expression of erythropoietin and erythropoietin receptor in peritoneal endometriosis
Author(s) -
Satoshi Matsuzaki,
М. Canis,
Ryo Yokomizo,
Nobuo Yaegashi,
M Bruhat,
K. Okamura
Publication year - 2003
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deg007
Subject(s) - endometriosis , erythropoietin , erythropoietin receptor , medicine , erythropoiesis , peritoneal fluid , pathogenesis , immunohistochemistry , endometrium , endocrinology , pathophysiology , anemia
Recent studies have indicated new physiological roles for erythropoietin (Epo) unrelated to erythropoiesis. We previously demonstrated that the Epo concentrations in peritoneal fluid from patients with stage I endometriosis were significantly higher than those with stages II, III and IV of the disease. Therefore, we hypothesized that Epo may play a role in the pathogenesis of endometriosis, particularly during the early stages of the disease.
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