Undetectable viral RNA in oocytes from SARS-CoV-2 positive women | Zendy

Montserrat Barragán | Zendy; Jaime Guillén | Zendy; N Martin-Palomino | Zendy; Amaia Rodrı́guez | Zendy; Rita Vassena | Zendy

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Undetectable viral RNA in oocytes from SARS-CoV-2 positive women

Author(s) -

Montserrat Barragán,

Jaime Guillén,

N Martin-Palomino,

Amaia Rodrı́guez,

Rita Vassena

Publication year - 2020

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deaa284

Subject(s) - covid-19 , virology , rna , biology , betacoronavirus , medicine , genetics , gene , outbreak , disease , infectious disease (medical specialty)

A central concern for the safe provision of ART during the current coronavirus disease 2019 (COVID-19) pandemic is the possibility of vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection through gametes and preimplantation embryos. Unfortunately, data on SARS-CoV-2 viral presence in oocytes of infected individuals are not available to date. We describe the case of two women who underwent controlled ovarian stimulation and tested positive to SARS-CoV-2 infection by PCR on the day of oocyte collection. The viral RNA for gene N was undetectable in all the oocytes analyzed from the two women.

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