A human oocyte with two sets of MII/PB-structures: Case report | Zendy

Thorir Hardarson | Zendy; Kersti Lundin | Zendy; Charles Hanson | Zendy

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A human oocyte with two sets of MII/PB-structures: Case report

Author(s) -

Thorir Hardarson,

Kersti Lundin,

Charles Hanson

Publication year - 2002

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/17.7.1892

Subject(s) - oocyte , zygote , metaphase , polar body , gene duplication , biology , andrology , genetics , chromosome , embryogenesis , embryo , medicine , gene

This paper reports a case where a normal-sized human oocyte has been documented having two polar bodies and two metaphase spindles. This finding suggests that the chromosomal content in oocytes of normal size may occasionally be duplicated and offers an additional explanation for the origin of triploid zygotes in humans. We speculate that this duplication may be caused by oocyte fusion at an early stage.

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