Open AccessMutation analysis of the inhibin alpha gene in a cohort of Italian women affected by ovarian failure
Author(s) -
Anna Marozzi,
Caterina A. M. La Porta,
Walter Vegetti,
Pier Giorgio Crosignani,
Maria Grazia Tibiletti,
Leda Dalprà,
Enrico Ginelli
Publication year - 2002
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/17.7.1741
Subject(s) - cohort , medicine , mutation , alpha (finance) , premature ovarian failure , gynecology , gene , genetics , biology , surgery , construct validity , patient satisfaction
Premature ovarian failure (POF) is a secondary hypergonadotrophic amenorrhoea affecting 1-3% of females, whose aetiology is almost unknown. However, inhibin alpha gene (INHalpha) has recently been indicated as candidate in POF pathogenesis.
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