Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss | Zendy

Howard Carp | Zendy; Ophira Salomon | Zendy; Daniel S. Seidman | Zendy; Rima Dardik | Zendy; Nurith Rosenberg | Zendy; Aida Inbal | Zendy

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Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss

Author(s) -

Howard Carp,

Ophira Salomon,

Daniel S. Seidman,

Rima Dardik,

Nurith Rosenberg,

Aida Inbal

Publication year - 2002

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/17.6.1633

Subject(s) - methylenetetrahydrofolate reductase , thrombophilia , medicine , factor v leiden , pregnancy , obstetrics , miscarriage , recurrent miscarriage , prothrombin g20210a , gynecology , venous thrombosis , gastroenterology , thrombosis , genetics , biology , genotype , gene

The genetic predispositions to venous thrombosis such as factor V Leiden (FVL) mutation (Arg 506 Gln), prothrombin (FII) gene mutation (G20210A), and mutation of the methylenetetrahydrofolate reductase (MTHFR) gene (C677T) have been reported to be associated with recurrent pregnancy loss. This paper examines the prevalence of markers for genetic thrombophilias in women with recurrent miscarriage.

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