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Ovarian hyperstimulation syndrome and assisted reproductive technologies: why some and not others?
Author(s) -
Bernie McElhinney,
Joy Ardill,
Carolyn Caldwell,
F. Lloyd,
Neil McClure
Publication year - 2002
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/17.6.1548
Subject(s) - ovarian hyperstimulation syndrome , follicular fluid , alpha (finance) , oocyte , vascular endothelial growth factor , endocrinology , medicine , embryo transfer , follicular phase , alpha 2 macroglobulin , vegf receptors , embryo , biology , andrology , gynecology , in vitro fertilisation , surgery , construct validity , patient satisfaction , microbiology and biotechnology , macroglobulin
alpha(2)-Macroglobulin (alpha(2)M) is a multifactorial binding protein, found in follicular fluid, that is a naturally occurring inhibitor of vascular endothelial growth factor (VEGF). The aim of this study was to determine if there is a relationship between serum VEGF levels, alpha(2)M levels and the development of OHSS in hyperstimulated subjects undergoing IVF (those with 15 or more oocytes).

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