Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women | Zendy

Noriko Kado | Zendy; Jo Kitawaki | Zendy; Hiroshi Obayashi | Zendy; Hiroaki Ishihara | Zendy; Hisato Koshiba | Zendy; Izumi Kusuki | Zendy; Katsumi Tsukamoto | Zendy; Goji Hasegawa | Zendy; Naoto Nakamura | Zendy; Toshikazu Yoshikawa | Zendy; Hideo Honjo | Zendy

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Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women

Author(s) -

Noriko Kado,

Jo Kitawaki,

Hiroshi Obayashi,

Hiroaki Ishihara,

Hisato Koshiba,

Izumi Kusuki,

Katsumi Tsukamoto,

Goji Hasegawa,

Naoto Nakamura,

Toshikazu Yoshikawa,

Hideo Honjo

Publication year - 2002

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/17.4.897

Subject(s) - endometriosis , genotype , adenomyosis , allele , polymorphism (computer science) , single nucleotide polymorphism , allele frequency , gene polymorphism , intron , medicine , gene , biology , genetics

To investigate whether polymorphisms of CYP17 and CYP19 genes are associated with the risk of endometriosis, we analysed the frequency and distribution of a single nucleotide polymorphism at the 5' untranslated region of the CYP17 gene, and a tetranucleotide (TTTA) tandem repeat polymorphism and a 3 bp insertion (I)/deletion (D) polymorphism in intron 4 of the CYP19 gene.

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