Peripheral blood mononuclear cells in early pregnancy promote invasion of human choriocarcinoma cell line, BeWo cells | Zendy

Haruto Egawa | Zendy; Hiroshi Fujiwara | Zendy; Takeshi Hirano | Zendy; Takahiro Nakayama | Zendy; Toshihiro Higuchi | Zendy; Keiji Tatsumi | Zendy; Takahide Mori | Zendy; Shingo Fujii | Zendy

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Peripheral blood mononuclear cells in early pregnancy promote invasion of human choriocarcinoma cell line, BeWo cells

Author(s) -

Haruto Egawa,

Hiroshi Fujiwara,

Takeshi Hirano,

Takahiro Nakayama,

Toshihiro Higuchi,

Keiji Tatsumi,

Takahide Mori,

Shingo Fujii

Publication year - 2002

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/17.2.473

Subject(s) - peripheral blood mononuclear cell , choriocarcinoma , peripheral blood , cell culture , pregnancy , andrology , medicine , biology , immunology , pathology , in vitro , genetics

During the establishment of the maternal blood circulation around the implanting human embryo, maternal peripheral blood mononuclear cells (PBMC) directly contact trophoblasts. To determine the physiological significance of this interaction, the effects of PBMC obtained from pregnant women on the proliferative and invasive properties of a human choriocarcinoma cell line, BeWo cells, were examined.

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