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Polycystic ovarian syndrome and thrombophilia
Author(s) -
G. Tsanadis
Publication year - 2002
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/17.2.314
Subject(s) - methylenetetrahydrofolate reductase , medicine , odds ratio , factor v leiden , thrombophilia , protein s , population , antithrombin , endocrinology , risk factor , factor v , protein c , genotype , venous thrombosis , biology , thrombosis , genetics , heparin , environmental health , gene
Polycystic ovarian syndrome (PCOS) is associated with insulin-induced plasminogen activator inhibitor-1 (PAI-1) elevations. Since thrombophilic states correlate with high miscariage rates, as does PCOS, this study aimed at looking for thrombophilic predisposition in PCOS women compared with non-PCOS controls.

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