Open AccessPossible interchromosomal effect in embryos generated by gametes from translocation carriers
Author(s) -
Luca Gianaroli
Publication year - 2002
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/17.12.3201
Subject(s) - chromosomal translocation , biology , aneuploidy , robertsonian translocation , embryo , genetics , chromosome , karyotype , preimplantation genetic diagnosis , andrology , medicine , gene
The incidence of abnormal pregnancies in carriers of balanced translocations depends strictly on the chromosomes involved in the translocations. The aim of this study was to verify whether conventional aneuploidy screening could be advantageously combined with preimplantation genetic diagnosis (PGD) for translocations.