Evidence for different aetiologies of low estradiol response to FSH: age-related accelerated luteinization of follicles or presence of ovarian autoantibodies
Author(s) -
Judith L. Luborsky,
P Thiruppathi,
Benjamin Rivnay,
R. Roussev,
C.B. Coulam,
Ewa Radwańska
Publication year - 2002
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/17.10.2641
Subject(s) - follicular fluid , medicine , endocrinology , follicular phase , ovary , follicle stimulating hormone , ovarian follicle , hormone , gonadotropin , biology , oocyte , luteinizing hormone , embryo , microbiology and biotechnology
We found granulosa cells of low responders (LR) expressed more LH receptors, suggesting that follicles were more luteinized than normal responders (NR). The objectives were to test the hypothesis that follicles of LR were more luteinized than follicles of NR, and to determine if LR with (LR+) and without (LR-) ovarian antibodies differed.
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