Biopsied testis cells of four 47,XXY patients: fluorescence in-situ hybridization and ICSI results | Zendy

Marianne Bergère | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Biopsied testis cells of four 47,XXY patients: fluorescence in-situ hybridization and ICSI results

Author(s) -

Marianne Bergère

Publication year - 2002

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/17.1.32

Subject(s) - aneuploidy , meiosis , fluorescence in situ hybridization , ploidy , biology , andrology , spermatogenesis , somatic cell , germ cell , in situ hybridization , microbiology and biotechnology , genetics , chromosome , medicine , endocrinology , gene , gene expression

A testis biopsy was performed for four non-mosaic 47,XXY azoospermic patients. Spermatozoa were found in three cases and frozen before ICSI. We analysed the various cells found in the four samples by multicolour fluorescence in-situ hybridization (FISH), to evaluate the meiosis and spermatogenesis possibilities of the 47,XXY and 46,XY testis cell lines, and to estimate aneuploidy rate in the resulting spermatids and spermatozoa.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research