Open AccessPolycystic ovarian syndrome and the risk of spontaneous abortion following assisted reproductive technology treatment
Author(s) -
Jim X. Wang,
Michael J. Davies,
Robert J. Norman
Publication year - 2001
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/16.12.2606
Subject(s) - medicine , body mass index , obstetrics , odds ratio , confounding , polycystic ovary , abortion , gynecology , pregnancy , population , confidence interval , infertility , cohort study , obesity , insulin resistance , biology , environmental health , genetics
A high proportion of infertile patients have polycystic ovarian syndrome (PCOS) with a reportedly greater risk of spontaneous abortion. Because of the close link between PCOS and obesity and the independent association of obesity with poor pregnancy outcomes, it is important to distinguish the possible confounding effect of body mass index (BMI) or other variables from that of PCOS. This study aims to determine the effect of PCOS status on the risk of spontaneous abortion with adjustment for body mass and several other confounding factors in a large cohort of pregnant infertile women.
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