Open AccessAntiphospholipid antibodies in women undergoing in-vitro fertilization
Author(s) -
Raj Rai,
Lesley Regan
Publication year - 1997
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/12.1.197
Subject(s) - unexplained infertility , medicine , in vitro fertilisation , recurrent miscarriage , antiphospholipid syndrome , pregnancy , infertility , miscarriage , obstetrics , antibody , gynecology , immunology , biology , genetics
Antiphospholipid antibodies have an established association with pregnancy complications such as recurrent miscarriage, growth retardation, placental abruption and stillbirth but their mechanism of action is unclear. We have investigated whether antiphospholipid antibodies occur more frequently in women having in-vitro fertilization (IVF) and whether their presence is associated with the likelihood of failed implantation. We studied 240 women undergoing IVF treatment who were