Immunology of human implantation: an evolutionary perspective
Author(s) -
Y.W. Loke,
Ashley King
Publication year - 1996
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/11.2.283
Subject(s) - allorecognition , conceptus , biology , perspective (graphical) , transplantation , immunity , immunology , fetus , pregnancy , evolutionary biology , medicine , immune system , genetics , computer science , t cell , artificial intelligence
The concept of the fetus as an allograft, which has been much cherished by reproductive immunologists, is in need of re-appraisal. We speculate that the relationship between the allogeneic conceptus and mother is not governed by the laws of classical transplantation immunity. Instead, this relationship is more akin to the allorecognition system seen in invertebrates.
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