The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations
Author(s) -
BJ Dunmore,
Kylie M. Drake,
Paul D. Upton,
Mark Toshner,
Micheala A. Aldred,
Nicholas W. Morrell
Publication year - 2013
Publication title -
human molecular genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.811
H-Index - 276
eISSN - 1460-2083
pISSN - 0964-6906
DOI - 10.1093/hmg/ddt492
Subject(s) - biology , chloroquine , microbiology and biotechnology , cell , mutation , gene , immunology , genetics , malaria
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