'Am not I a fly like thee?' From genes in fruit flies to behavior in humans
Author(s) -
Ralph J. Greenspan
Publication year - 2004
Publication title -
human molecular genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.811
H-Index - 276
eISSN - 1460-2083
pISSN - 0964-6906
DOI - 10.1093/hmg/ddh248
Subject(s) - biology , drosophila melanogaster , drosophila (subgenus) , gene , evolutionary biology , genetics , melanogaster , mutant
The fruit fly Drosophila melanogaster has provided insight into the role of genes in behavior, some of which have relevant implications for humans. Mutants induced or engineered in the laboratory have contributed to our understanding of biological rhythms, learning, memory, neurodegenerative disease and drug response. Studies of naturally occurring genetic variation in behavior have advanced our understanding of what kinds of variants arise spontaneously and contribute to behavior.
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