Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2 | Zendy

S. Tyler Hollmig | Zendy; Kiyoshi Ariizumi | Zendy; P.D. Cruz | Zendy

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Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2

Author(s) -

S. Tyler Hollmig,

Kiyoshi Ariizumi,

P.D. Cruz

Publication year - 2009

Publication title -

glycobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.757

H-Index - 128

eISSN - 1460-2423

pISSN - 0959-6658

DOI - 10.1093/glycob/cwp032

Subject(s) - c type lectin , receptor , lectin , transmembrane protein , pattern recognition receptor , immunity , biology , microbiology and biotechnology , chemistry , immune system , biochemistry , immunology , innate immune system

The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin receptors and a focus on the roles of dectin-1 and dectin-2 in anti-fungal immunity.

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