Open AccessA genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers
Author(s) -
Nikolai Hecker,
Michael Hiller
Publication year - 2020
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giz159
Subject(s) - enhancer , genome , biology , computational biology , placenta , evolutionary biology , genetics , gene , pregnancy , gene expression , fetus
Multiple alignments of mammalian genomes have been the basis of many comparative genomic studies aiming at annotating genes, detecting regions under evolutionary constraint, and studying genome evolution. A key factor that affects the power of comparative analyses is the number of species included in a genome alignment.
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