Prognostic model for multiple myeloma progression integrating gene expression and clinical features
Author(s) -
Chen Sun,
Hongyang Li,
Ryan E. Mills,
Yuanfang Guan
Publication year - 2019
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giz153
Subject(s) - proportional hazards model , multiple myeloma , progression free survival , monoclonal gammopathy of undetermined significance , biomarker , computer science , hazard ratio , tumor progression , medicine , survival analysis , computational biology , machine learning , artificial intelligence , cancer , bioinformatics , oncology , biology , overall survival , immunology , genetics , monoclonal , confidence interval , antibody , monoclonal antibody
Multiple myeloma (MM) is a hematological cancer caused by abnormal accumulation of monoclonal plasma cells in bone marrow. With the increase in treatment options, risk-adapted therapy is becoming more and more important. Survival analysis is commonly applied to study progression or other events of interest and stratify the risk of patients.
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