SeQuiLa-cov: A fast and scalable library for depth of coverage calculations
Author(s) -
Marek Wiewiórka,
Agnieszka Szmurło,
Wiktor Kuśmirek,
Tomasz Gambin
Publication year - 2019
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giz094
Subject(s) - computer science , scalability , preprocessor , speedup , exome , pipeline transport , distributed computing , data mining , parallel computing , exome sequencing , database , artificial intelligence , biology , biochemistry , environmental engineering , engineering , mutation , gene
Depth of coverage calculation is an important and computationally intensive preprocessing step in a variety of next-generation sequencing pipelines, including the analysis of RNA-sequencing data, detection of copy number variants, or quality control procedures.
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